Originally established by the Government of Kerala as an advanced centre for medical specialties, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST) metamorphosed into an Institute of National Importance with the status of a University in 1980 under the Department of Science and Technology, Govt. of India by an Act of Parliament (Act 52 of 1980). The joint culture of medicine and technology that the Institute pioneered more than three decades ago has come of age and gained unprecedented acceptance in India. Imbued with an inclination to venture into less-trodden domains, the Institute focuses on patient care of high quality, technology development of industrial significance and health research studies of social relevance. The emphasis is on development of facilities less readily available elsewhere in the country such as interventional radiology, cardiac electrophysiology, presurgical evaluation and surgery for epilepsy, microsurgery and deep brain stimulation for movement disorders, new biomedical devices and products, evaluation of medical devices to global specifications, new academic programmes and global public health networks.